Oxytocin Acetate 2mg

1. What is Oxytocin Acetate?

Oxytocin Acetate is a synthetic version of the natural hormone oxytocin, which plays a key role in childbirth, lactation, and emotional bonding. It is often used in clinical settings to induce labor, manage postpartum bleeding, and promote lactation. Oxytocin Acetate works by stimulating the contraction of smooth muscles in the uterus and aiding in the release of milk from the mammary glands. Additionally, it has been studied for its potential in treating anxiety, depression, and social bonding disorders.

2. Oxytocin Acetate Structure

【pictures linking，https://pubchem.ncbi.nlm.nih.gov/compound/439302】

Sequence:Cys(1)-Tyr-lle-GIn-Asn-Cys(1)-Pro-Leu-Gly

Molecular Formula: C45H70N12O14S2

Molecular Weight: 1067.24 g/mol

CAS Number: 50-56-6

Synonyms: Pitocin,Endopituitrina, Ocytocin

3. Oxytocin Acetate Research

Oxytocin Acetate is the acetate-salt form of oxytocin, a nonapeptide hormone/neuropeptide primarily synthesized in the hypothalamus and released by the posterior pituitary. Historically, it’s known for labor induction and milk ejection, but recent research highlights its diverse roles in social bonding, anxiety, pain modulation, metabolism, and immune health 【https://en.wikipedia.org/wiki/Oxytocin?utm_source=chatgpt.com】.

【1】Molecular & Receptor Signaling

Binds to oxytocin receptors (OTR)—a Gₚ-coupled receptor—activating multiple intracellular cascades: PLC/IP₃/DAG, Ca²⁺ release, PKC/MAPK, PKA, PI3K/NO, Rho-kinase, influencing muscle contraction, cell growth, inflammation, and neurotransmission 【https://pmc.ncbi.nlm.nih.gov/articles/PMC2972642/?utm_source=chatgpt.com】.

Oxytocinase enzymes (leucyl/cystinyl aminopeptidase) degrade oxytocin, regulating its levels—especially during pregnancy 【https://en.wikipedia.org/wiki/Oxytocinase?utm_source=chatgpt.com】.

【2】 Central Nervous System Effects

Intranasal Oxytocin crosses the olfactory/trigeminal pathways, delivering functional peptide to the brain’s social and reward circuitry (e.g., amygdala, striatum, prefrontal cortex) within hours 【https://www.nature.com/articles/s41467-020-15942-1?utm_source=chatgpt.com】.

Neuropsychiatric applications include modulation of autism, social anxiety, PTSD, schizophrenia, addiction, and depression【https://pmc.ncbi.nlm.nih.gov/articles/PMC5862033/?utm_source=chatgpt.com】.

Demonstrates analgesic and antinociceptive effects via spinal and supraspinal pathways, likely through OTR and opioid receptor modulations 【https://en.wikipedia.org/wiki/Lipo-oxytocin-1?utm_source=chatgpt.com】.

【3】 Metabolic & Energy Regulation

Suppresses appetite and food intake after both peripheral and central administration in rodents and humans; effect amplified in obesity 【https://pmc.ncbi.nlm.nih.gov/articles/PMC6608564/?utm_source=chatgpt.com】.

Enhances thermogenesis and energy expenditure in animal models, and improves glycemic control by modulating insulin and glucagon 【https://pmc.ncbi.nlm.nih.gov/articles/PMC6608564/?utm_source=chatgpt.com】.

【4】 Immune & Anti-Inflammatory Effects

Potently inhibits pro-inflammatory cytokines (e.g., TNFα) and supports anti-sepsis protection in pre-clinical sepsis models 【https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2022.864007/full?utm_source=chatgpt.com】.

Demonstrated tissue-protective effects in organs affected by inflammation and ischemia.

✅ Why Consider Oxytocin Acetate?

🧘 Emotional & social enhancement: promotes bonding, trust, maternal behavior, and reduces anxiety.

🩹 Natural analgesic: alleviates pain and reduces opioid usage via neuropeptide signaling.

🍽 Metabolic regulator: suppresses appetite, induces calorie reduction, supports weight and glycemic control .

🔥 Boosts energy: enhances thermogenesis, insulin sensitivity—beneficial in obesity and metabolic disorders .

🛡 Immune modulator: counters cytokine storms, supports tissue resilience in systemic inflammation .

🇬🇧 Flexible delivery: FDA-approved IV/IM forms for obstetrics; intranasal and oromucosal formulations facilitate psychiatric and metabolic use .

4. Future Oxytocin Acetate Research

Enhanced Brain Delivery & Small Molecule Agonists

Development of non-peptide OTR agonists like LIT-001 with improved blood–brain barrier penetration, oral bioavailability, and CNS-targeting efficacy 【https://en.wikipedia.org/wiki/LIT-001?utm_source=chatgpt.com】.

Lipidated Long-Acting Analogs

Lipo-oxytocin-1 (LOT1)—palmitoylated version—demonstrates prolonged social, anxiolytic benefits in rodent models, offering promise for sustained-release therapeutics .

Oral/Oromucosal Peptide Formulations

“Oxipops” research highlights favorable pharmacokinetics and systemic absorption, enabling more accessible administration routes 【https://www.nature.com/articles/s41392-022-00904-4?utm_source=chatgpt.com】.

Metabolic & Obesity Trials

Testing OTxN analogs in combination with compounds like naltrexone to tackle hypothalamic obesity and metabolic syndrome in clinical settings 【https://pmc.ncbi.nlm.nih.gov/articles/PMC6608564/?utm_source=chatgpt.com】.

Pain, Addiction & Psychiatric Expansion

Ongoing research into OTR agonists for chronic pain, alcohol use disorder, PTSD, autism, social anxiety, and other neurobehavioral conditions .

Sepsis & Organ Protection

Early stage human trials may investigate oxytocin’s efficacy in sepsis, ischemia-reperfusion injury, and organ failure based on robust animal data .

5. Application Areas

Obstetrics & Lactation: standardized IV/IM oxytocin remains essential for labor management and postpartum hemorrhage .

Psychiatric & Neurodevelopment: adjunctive treatment for autism, social anxiety, PTSD, depression, and trust disorders via intranasal or oral forms.

Pain Management: alternative to opioids in neuropathic and chronic pain models.

Metabolic & Weight Control: appetite suppression and metabolic benefits, particularly in obese populations.

Immunomodulation: counteracting cytokine storms and supporting sepsis care in acute inflammatory states.

Cardiovascular & Thermoregulation: supports vascular health and body temperature balance.

✅ Summary

Oxytocin Acetate transcends its traditional roles in childbirth and lactation. As a neuropeptide, it cultivates social connectivity, relieves pain, regulates metabolism, modulates immunity, and protects tissues. With innovative delivery technologies—lipidation, oral/mucosal formulations, CNS-permeable agonists—oxytocin may shift from hospital use to everyday wellness, mental health, metabolic support, and immune resilience therapies.

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The products offered on this website are furnished for in-vitro studies only. In-vitro studies(Latin: in glass) are performed outside of the body. These products are not medicines or drugs and have not been approved by the FDA to prevent, treat or cure any medical condition, ailment or disease. Bodily introduction of any kind into humans or animals is strictly forbidden by law.